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Gallbladder cancer is a rare form of cancer. Gallbladder cancer refers to the abnormal growth of cells in the gallbladder. It originates in the gallbladder's innermost layer, known as the mucosal layer, then spreads outward.
The gallbladder, a small pear-shaped organ under the liver, stores bile. Bile aids the liver in digesting fats from the food we consume.
Gallbladder cancer is rare, with a low recovery rate, because gallbladder cancer starts to show symptoms when it reaches an advanced stage and sometimes shows no symptoms.
Statistics
Gallbladder cancer is relatively unknown to many people. It is the 22nd most common cancer worldwide. It ranks as the 20th most common cancer among women and the 23rd most common cancer among men.
Risk factors and symptoms
- Sex (more common in females)
- Ethnicity (American Indian, Alaskan native, or Mexican-American)
- 65 years old or more
- History of gallstones
- Gallbladder polyps
- Chronic gallbladder inflammation
- Porcelain gallbladder (calcium deposition in the gallbladder)
- Choledochal cyst
- Abnormalities of the bile ducts
- Primary sclerosing cholangitis
- Obesity
- Typhoid
Symptoms of gallbladder cancer may vary, ranging from none to appearing at an advanced stage. We may consider these symptoms as alarming for gallbladder cancer-upper abdominal pain, jaundice, lumps in the abdomen, unexplained weight loss, nausea, vomiting, bloating, fever, loss of appetite, and aching pain in the right side of the tummy.
Prevention
Preventing gallbladder cancer is not possible, but adopting healthy habits can reduce the risk of developing it.
- Maintain a healthy weight
- Regular physical activity
- Healthy eating habits
- Avoid alcohol consumption
- Don’t smoke
Treatment
Treatments are available for early-stage gallbladder cancer, like-
- Surgery
Surgery has the best treatment outcomes. A surgical oncologist may perform a cholecystectomy, which involves removing the gallbladder or adjacent tissues. - Radiation therapy
The radiation kills the cancer cells or slows the growth of the tumor. - Chemotherapy
Chemotherapy uses drugs to kill cancer or stop its proliferation. - Targeted therapy
It targets specific cancer cells that carry certain gene mutations. - Immunotherapy
It boosts the immune system and destroys cancer cells.